Cold Case: The Tylenol Murders revisits the 1982 cyanide-laced pill killings in a chilling docuseries that questions if the true killer was ever found.
A notorious unsolved mystery that once rocked the nation is about to take center stage again. Cold Case: The Tylenol Murders, a chilling new three-part docuseries on Netflix, will premiere May 26, 2025, offering a deep dive into one of America’s most infamous unsolved crimes.
Directed by Yotam Guendelman and Ari Pines—the filmmaking duo behind Shadow of Truth and Buried—and executive produced by true crime heavyweight Joe Berlinger (Cold Case: Who Killed JonBenét Ramsey, Conversations with a Killer), this series revisits the 1982 Tylenol poisonings that gripped the country with fear and changed the way we consume medicine forever.
The docuseries transports viewers back to Chicago in 1982, when at least seven people died after unknowingly ingesting cyanide-laced Tylenol capsules. The deaths sparked a national panic and launched one of the largest criminal investigations in U.S. history. What unfolded was not just a whodunit, but a reckoning over public safety, product tampering, and the limits of investigative power.
Cold Case: The Tylenol Murders dives deep into the mystery that turned the world’s best-selling over-the-counter painkiller into a symbol of danger and distrust. As the series questions whether a single mastermind orchestrated the poisonings or if that narrative was part of a larger cover-up, it opens new avenues of speculation around corporate responsibility, media pressure, and law enforcement’s race for answers.
The series is produced by RadicalMedia Production and MA and Silvio Films Production, in association with Third Eye Motion Picture Company. Alongside Berlinger, executive producers include Jon Kamen, Jen Isaacson, Craig D’Entrone, Yotam Guendelman, Ari Pines, Mika Timor, Maor Azran, and Dan Adler.
With its premiere just around the corner, Cold Case: The Tylenol Murders promises to reawaken national interest in a case that’s haunted the collective memory for over four decades—and raise new questions about whether justice was ever truly served.
